$32000.0 Buy It Now or Best Offer
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(398) 100%,
Location: Rocklin, California
Ships to: US,
Item: 186257897463
Restocking Fee:No
Return shipping will be paid by:Seller
All returns accepted:Returns Accepted
Item must be returned within:60 Days
Refund will be given as:Money Back
Wyatt Technology:Wyatt Technology
MicroDAWN, microOptilab:MicroDAWN, microOptilab
MPN:WMD3-01, WOP1-01
Waters Wyatt Technology microDAWN + microOptilab Detector for UHPLC w/Warranty60-day return warranty Feedback NO NEED FOR NEGATIVE OR NEUTRAL FEEDBACK. If there is a problem, please contact us before leaving feedback. If an item arrived not as described or you are not satisfied with the item or shipping time, we will resolve all issues. We strive for a 5-star detailed seller rating and work hard for our customer’s satisfaction by providing a smooth transaction. Payment Full payment is due within 3 days. Preferred payment method is PayPal. We do accept card payment at. We may process your payment as per your organizations policy if needed, for specific payment needs or company invoice please or us at. Shipping — Items ship within 1-2 business days after payment. — We ship with USPS FedEx UPS — If you wish to use your FedEx UPS account# please let us know upon purchase. — We ship Worldwide. Buyer responsible for customs/duty import charges.Return PolicyWe offer a 30-day return on all products, if item arrives damaged or not as described or due to any error on our part, we will refund the full amount with ship charges both ways. If buyer decides to return an item for any other reason, in this case the buyer pays return shipping. microDAWN The Only Multi-Angle Light Scattering Detector for UHPLC.UHPLC-SEC SystemThe microDAWN® can be coupled to any UHPLC-SEC system to determine absolute molecular weights and sizes of polymers, peptides, or proteins directly, without resorting to column calibration or reference standards. The microDAWN produces minimal band broadening in order to maintain the narrow peaks typical of UHPLC, while meeting or exceeding the sensitivity of the miniDAWN®.Polymer CharacterizationRead our paper published in Nature Scientific Reports: “Measuring proteins with greater speed and resolution while reducing sample size”. The microDAWN MALS detector performs absolute characterization of macromolecules eluting from UHPLC, determining molar mass and size independently of retention time and molecular reference standards. This instrument offers superb sensitivity over a wide range of molar mass, size and concentrations. In most respects the microDAWN is similar to the well-established miniDAWN, a workhorse MALS instrument used in hundreds of labs around the world for characterizing proteins and other molecules smaller than 50 nm in radius.Distinctly from the miniDAWN, the microDAWN is uniquely suitable for use in conjunction with UHPLC Size Exclusion Chromatography (SEC-MALS) thanks to its small interdetector dispersion. In some cases it may be used with ion-exchange or other types of chromatography. Regardless of the specifics, the microDAWN produces minimal band broadening in order to maintain the narrow peaks typical of UHPLC.Mw from 200 Da to 10 MDaSensitivity: 1.0 µg/mL BSA (66.4 kDa) in PBS; 50 ng/mL 100 kDa polystyrene in THF.Rg from 10 to 50 nmUltra-stable laserThe microDAWN and its companion microOptilab™Refractive Index Detector interface to most standard UHPLC systems. As these detectors are based on the advanced technology of Wyatt’s miniDAWN and Optilab®, respectively, users may be confident in the underlying capabilities cited in thousands of peer-reviewed publications.Ultrasonic Cleaning IncludedEach microDAWN includes a COMET™ ultrasonic transducer that cleans MALS flow cells automatically by agitating the fluid and loosening particles from the glass surfaces. microOptilab Universal Detection for UHPLC and SEC-MALSIndependent of ChromaphoresIndependent of chromaphores or fluorophores, differential Refractive Index (dRI) detectors measure concentrations of all types of samples in almost all solvents. The microOptilab™ brings the universal detection capabilities, unsurpassed concentration range, and superb sensitivity and linearity – familiar from the Optilab® – to the domain of UHPLC.SEC-MALS with UHPLCLike standard SEC, UHPLC-SEC analysis relying on column calibration with molecular standards is unreliable when the standards do not accurately reflect your samples in terms of conformation, non-ideal (e.g., hydrophobic) column interactions or reversible association. SEC-MALS employs a microDAWN® MALS detector downstream of the SEC column and UV detector, to determine molar mass / molecular weight distributions of macromolecules independently of column calibration.Refractive index detection is an important component of any SEC-MALS system, and necessary for analyzing conjugated proteins or polymers devoid of chromaphores. The microOptilab connects with the microDAWN MALS detector for a complete UHP-SEC-MALS setup that transfers the many benefits of SEC-MALS analysis to the realm of UHPLC.Key benefitsVery low band broadening, < 4 µL, to maintain the resolution of very narrow UHPLC peaksExtraordinary dRI measurement range, -4.7 x 10-3 to +4.7 x 10-3 RIU (comparable to 25 mg/mL protein in PBS)Highly sensitive, ± 1.5 x 10-9 RIU across the entire measurement rangeMeasures solvent refractive index, require for MALS calculationsMeasures at the same wavelength as the MALS detector, for maximum accuracy in MALS calculationsTemperature range 4 °C to 65 °C for proteins and polymers that require a range of temperaturesHigh-resolution, touch-screen front panel displays data graphs and instrument diagnostics, even with the host computer turned offUnparalleled featuresConsidering the extremely small peak volumes of UHPLC, band broadening in the microOptilab is kept to the absolute minimum, at less than 4 µL, as compared to 20 - 40 µL or more for standard RI detectors. As a result, the superior resolution from UHPLC columns and instruments will not be compromised with the microOptilab RI detector.Even though the microOptilab offers a dRI measurement range orders of magnitude beyond that of other UHPLC dRI detectors, unlike other detectors there are no range or gain settings in the microOptilab. The full range of instrument detection is always present, and the full sensitivity exists over the entire range. The small flow cell and proprietary temperature regulation enable stable RI baselines and signals which further enhance the detector's sensitivity.Unlike all other dRI detectors, the microOptilab also measures absolute refractive index in order to determine solvent RI, necessary in light scattering calculations and useful in assessing the accuracy of mixing of solvent gradients.The microOptilab can be operated below ambient temperatures as easily as above ambient. No hassle temperature control can be programmed down to 4 °C or as high as 65 °C.The microOptilab is compatible with all UHPLC systems.
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